The main laboratory abnormalities noted in COVID-19 patients are anemia, leukopenia particularly lymphopenia, and leukocytosis including neutrophilia and monocytosis . Lymphopenia was associated with severe COVID-19 (OR 3.70 [2.44, 5.63], p < 0.001; I2 40%). The impact of lymphopenia on disease severity and mortality is most significant in elderly populations. Neutrophilia, lymphocytopenia, low CD4 + T cells, and decreased C3 were immunity-related risk factors predicting mortality of patients with COVID-19. Meta-regression showed that the association between lymphocyte count and composite poor outcome was affected by age (p = 0.034). The patient has since been discharged and is recovering at home. Most individuals with COVID-19 infection (∼80%) have been reported to have uncomplicated disease with mild symptoms, and only a subset develop severe disease requiring hospitalization. In conclusion, lymphopenia is an effective and reliable indicator of the severity and hospitalization in COVID-19 patients. Relationship between changes in the course of COVID-19 and ratio of neutrophils-to-lymphocytes and related parameters in patients with severe vs. common disease - Volume 149 3,4 The most common initial symptoms in confirmed COVID-19 infected patients were fever, cough, dyspnea, and fatigue, 4–8 with fever reportedly less common than in SARS-CoV (99%) and MERS-CoV (98%). This meta-analysis showed that lymphopenia on admission was associated with poor outcome in patients with COVID-19. Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses. In our study, anemia was the most common finding, followed by neutrophilia, neutrophilic left shift, and lymphopenia. Therefore, older age and lymphopenia may be used in combination to predict poor progno­sis in COVID-19 patients. https://www.frontiersin.org/articles/10.3389/fimmu.2020.02063 Introduction Coronavirus disease 2019 (COVID-19) has declared as a pandemic on 12 March, 2020. Lymphopenia was seen in 18 (82%) patients who died of COVID 19, with moderate lymphopenia present in 13 (59%) and severe lymphopenia present in 5 (22.7%) patients. We suggest that TLM should be included in … Introduction Neutrophilia was seen in both groups with median ANC of 7.2 x 109/l in mortality patients and 4.2 x 109/l in recovered group (p <0.01). coronavirus, COVID-19, lymphocyte count, lymphopenia, elderly. Neutrophils play a critical function in the clearance of bacteria with specific mechanisms to combat viruses. COVID-19 testing and suspicion of leukemia “We hope to avoid unnecessary blood work-up and diagnostic testing in patients with COVID-19,” Graff said. As the patient got better, the neutrophilia resolved, and the other blood indicators were back to normal ranges. Keywords. Introduction Outbreak of corona virus disease in 2019 (COVID‐19) has resulted in significant morbidity and mortality worldwide. Coronavirus disease 2019 (COVID-19) is a virus-induced respiratory disease that may progress to acute respiratory distress syndrome (ARDS) and is triggered by immunopathological mechanisms that cause excessive inflammation and leukocyte dysfunction.

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