Therefore, glucose is very important for the energetic metabolism of red blood cells, and glucose transporters are vital protein structures for red blood cells to receive extracellular glucose. The cytoplasm of erythrocytes is rich in hemoglobin, the protein that carries oxygen. In contrast to mammalian erythrocytes, which have lost their nucleus and mitochondria during maturation, the erythrocytes of almost all other vertebrate species are nucleated throughout their lifespan. Advantages. Adults have around 25 trillion red blood cells in circulation at any given time. Cells that require a lot of energy, such as muscle cells, can contain hundreds or thousands of mitochondria. Mitochondria are found in the cells of nearly every eukaryotic organism, including plants and animals. In humans (and all mammals), red blood cells lack mitochondria and therefore has no functional TCA cycle. Mature mammalian red blood cells, called erythrocytes, have no nucleus, ribosomes, or mitochondria. Red blood cells do not have mitochondria or any of the organelles that are seen in the majority of other cells in the body. The blood’s red color is due to the spectral properties of the hemic iron ions in hemoglobin. Red blood cells do not contain RNA or DNA like most other cells in the body. Red Blood Cell Extrudes Nucleus and Mitochondria Against Oxidative Stress by Zhong-Wei Zhang , et al. Question: 1) Red Blood Cells Do Not Contain Mitochondria. Red blood cells are really not complete cells at all. Mammals have no mitochondria in their red blood cells, but birds do, and according to the research team from Lund and Glasgow this means that the blood can function as … Red blood cells circulate on average for about four months. A few types of cells, such as red blood cells, lack mitochondria entirely. 2. Red blood cells are considered cells, but they lack a nucleus, DNA, and organelles like the endoplasmic reticulum or mitochondria. Red blood cells cannot divide or replicate like other bodily cells. They metabolize glucose mainly via glycolysis, forming lactate which is released from the cells; this yields 2 ATP for each glucose molecule, much less than complete oxidation (ca 30 ATP), but enough to support the red blood cells' energy needs. They are fragments of cells that have a specific action, transporting oxygen and carbon dioxide. Red blood cells do not have mitochondria, so they rely exclusively on glycolysis and glucose for energy. They do not contain a nucleus nor much of the cellular components of other cells. After all, red blood cells have to come from somewhere, and cells do need mitochondria and a nucleus with DNA to go through mitosis, make new cells, and make all of that hemoglobin protein. All of this other material would reduce the efficiency of the production of red cells and increase their volume. 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